Lung Transplant in Infants Under the age of 2. Analysis of More than 2 Decades of Experience
This webinar will be on May 11, 2027 (16:00 CET)
The idea of the presentation would be to analyse our data regarding the infants with a lung transplant under the age of 2 and to review the international experience about the subject.
Our aim is to describe the follow-up of the infants <2 years of age that received a lung transplant at our hospital, comparing their survival with older children.
Methods: retrospective review (August 2000 to June 2025) describing the clinical characteristics of the 12 infants that underwent a lung transplant under the age of 2, including their previous situation, the complications associated to the procedure and their survival using Kaplan-Meier analysis.
Results:
- The average age at the time of the transplant (Tx) was 13.5 months (range: 4.2-22.8), and the average weight was 7.4 kg (range: 3.7 – 14). The average waiting time was 132 days (range: 7-344).
– Most of the patients were admitted in the hospital (83%) and needed continuous respiratory support (83%) before the Tx.
– Most of these lung Tx recipients had a significant airway complication (67%) that needed interventional treatment or prolonged mechanical ventilation.
– Median survival of these infants was 7.86 years. The 1-year, 5-years and 10-years survival was 83%, 65% and 46%, respectively.
Speaker:
·Dr Ignacio Iglesias, Paediatric Pneumology and Cystic Fibrosis Unit at Vall d’Hebron University Hospital, Barcelona, Spain.
Learning outcomes:
After attending the webinar participants will be able to understand/ learn that:
- Lung transplantation is feasible in small children with severe and end-stage respiratory diseases
- The most significant complications after a lung transplant at the youngest age are, in our experience, related to infections and airway disorders such as tracheobronchial stenosis and malacia
- Infants that underwent a lung transplantation under the age of 2 have a non-inferior survival compared to other periods of the childhood